Search results for "Gadolinium"

showing 10 items of 303 documents

CCDC 866944: Experimental Crystal Structure Determination

2013

Related Article: E.Colacio, J.Ruiz, A.J.Mota, M.A.Palacios, E.Ruiz, E.Cremades, M.M.Hanninen, R.Sillanpaa, E.K.Brechin|2012|Comptes Rendus Chimie|15|878|doi:10.1016/j.crci.2012.08.001

(mu~2~-22'-((methylimino)bis(ethane-21-diyl(methylimino)methylene))bis(4-methyl-6-methoxyphenolato))-tris(nitrato)-aqua-cobalt-gadolinium hydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

Preparation and Characterization of Nanocrystalline Gadolinium Oxide Powders and Films

2020

Due to its magnetic, electrical, absorption, and emission properties, nanoscale gadolinium oxide is widely used in various fields. In this research, nanocrystalline Gd2O3 powders and films on glass substrates have been produced by the extraction-pyrolytic method. X-ray diffraction analysis revealed the formation of single phase Gd2O3 with cubic crystal structure and the mean crystallite size from 9 to 25 nm in all produced materials. The morphology of samples has been characterized by scanning electron microscopy and transmission electron microscopy.

010302 applied physicsMaterials scienceMorphology (linguistics)Mechanical Engineering02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesNanocrystalline materialCharacterization (materials science)Chemical engineeringMechanics of MaterialsLiquid–liquid extraction0103 physical sciencesGeneral Materials ScienceGadolinium oxide0210 nano-technologyPyrolysisKey Engineering Materials
researchProduct

Effects of exposure to gadolinium on the development of geographically and phylogenetically distant sea urchins species.

2016

Gadolinium (Gd), a metal of the lanthanide series used as contrast agent for magnetic resonance imaging, is released into the aquatic environment. We investigated the effects of Gd on the development of four sea urchin species: two from Europe, Paracentrotus lividus and Arbacia lixula, and two from Australia, Heliocidaris tuberculata and Centrostephanus rodgersii. Exposure to Gd from fertilization resulted in inhibition or alteration of skeleton growth in the plutei. The similar morphological response to Gd in the four species indicates a similar mechanism underlying abnormal skeletogenesis. Sensitivity to Gd greatly varied, with the EC50 ranging from 56 nM to 132 μM across the four species…

0301 basic medicineGadoliniumved/biology.organism_classification_rank.specieschemistry.chemical_elementGadolinium010501 environmental sciencesAquatic ScienceEcotoxicologyOceanography01 natural sciencesParacentrotus lividusEnvironmental impact03 medical and health sciencesDevelopmental abnormalityEchinoid; Embryos; Skeletogenesis; Developmental abnormality; Medical drugs; Ecotoxicology; Environmental impactbiology.animalEcotoxicologyAnimalsCentrostephanus rodgersiiSettore BIO/06 - Anatomia Comparata E CitologiaArbacia lixulaSea urchin0105 earth and related environmental sciencesArbaciaLarvabiologyEcologyved/biologyGeneral Medicinebiology.organism_classificationPollutionPhylogeographySkeletogenesi030104 developmental biologyMedical drugchemistryEmbryoAquatic environmentSea UrchinsParacentrotusEchinoidWater Pollutants ChemicalEnvironmental MonitoringMarine environmental research
researchProduct

The morphogenetically active polymer, inorganic polyphosphate complexed with GdCl 3 , as an inducer of hydroxyapatite formation in vitro

2015

Inorganic polyphosphate (polyP) is a physiological polymer composed of tens to hundreds of phosphate units linked together via phosphoanhydride bonds. Here we compared the biological activity of polyP (chain length of 40 phosphate units), complexed with Gd(3+) (polyP·Gd), with the one caused by polyP (as calcium salt) and by GdCl3 alone, regarding their potencies to induce hydroxyapatite (HA) formation in SaOS-2 cells in vitro. The three compounds, GdCl3, polyP and polyP·Gd were found to be non-toxic at concentrations up to at least 30μM. Selecting a low, 5μM, concentration it was found that polyP·Gd significantly induced HA formation, as determined by Alizarin Red S staining and by quantit…

0301 basic medicinePolymerschemistry.chemical_elementGadolinium02 engineering and technologyCalciumBiochemistry03 medical and health scienceschemistry.chemical_compoundPolyphosphatesCell Line Tumorotorhinolaryngologic diseasesHumansneoplasmsSaos-2 cellsPharmacologychemistry.chemical_classificationDose-Response Relationship DrugChemistryPolyphosphateBiological activitypathological conditions signs and symptoms021001 nanoscience & nanotechnologyPhosphatedigestive system diseasesIn vitroDurapatitesurgical procedures operative030104 developmental biologyEnzymeBiochemistryAlkaline phosphatase0210 nano-technologyBiochemical Pharmacology
researchProduct

Induction of skeletal abnormalities and autophagy in Paracentrotus lividus sea urchin embryos exposed to gadolinium.

2017

Abstract Gadolinium (Gd) concentration is constantly increasing in the aquatic environment, becoming an emergent environmental pollutant. We investigated the effects of Gd on Paracentrotus lividus sea urchin embryos, focusing on skeletogenesis and autophagy. We observed a delay of biomineral deposition at 24 hours post fertilization (hpf), and a strong impairment of skeleton growth at 48 hpf, frequently displayed by an asymmetrical pattern. Skeleton growth was found partially resumed in recovery experiments. The mesodermal cells designated to biomineralization were found correctly migrated at 24 hpf, but not at 48 hpf. Western blot analysis showed an increase of the LC3-II autophagic marker…

0301 basic medicineSea urchinWater Pollutants Radioactiveanimal structuresEmbryo NonmammalianMorphogenesisGadolinium010501 environmental sciencesAquatic ScienceEcotoxicologyOceanography01 natural sciencesParacentrotus lividuslaw.inventionEnvironmental impact03 medical and health sciencesDevelopmental abnormalityWestern blotConfocal microscopylawbiology.animalmedicineAutophagyAnimalsSettore BIO/06 - Anatomia Comparata E CitologiaSea urchin0105 earth and related environmental sciencesbiologymedicine.diagnostic_testMetalfungiAutophagyEmbryoGeneral MedicineAnatomybiology.organism_classificationSkeleton (computer programming)PollutionCell biology030104 developmental biologySkeletogenesiMedical drugEmbryoembryonic structuresParacentrotusMarine environmental research
researchProduct

Gadolinium perturbs expression of skeletogenic genes, calcium uptake and larval development in phylogenetically distant sea urchin species

2018

Chelates of Gadolinium (Gd), a lanthanide metal, are employed as contrast agents for magnetic resonance imaging and are released into the aquatic environment where they are an emerging contaminant. We studied the effects of environmentally relevant Gd concentrations on the development of two phylogenetically and geographically distant sea urchin species: the Mediterranean Paracentrotus lividus and the Australian Heliocidaris tuberculata. We found a general delay of embryo development at 24 h post-fertilization, and a strong inhibition of skeleton growth at 48 h. Total Gd and Ca content in the larvae showed a time- and concentration-dependent increase in Gd, in parallel with a reduction in C…

0301 basic medicineVascular Endothelial Growth Factor AHealth Toxicology and MutagenesisGadoliniumchemistry.chemical_elementEmbryonic DevelopmentGadolinium010501 environmental sciencesAquatic ScienceMarine pollutionReal-Time Polymerase Chain ReactionEcotoxicology01 natural sciencesParacentrotus lividus03 medical and health sciencesMedical agentTransforming Growth Factor betabiology.animalSkeletogenesisAnimalsAnthocidarisAxis specificationSettore BIO/06 - Anatomia Comparata E CitologiaSea urchin embryoSea urchinGenePhylogeny0105 earth and related environmental sciencesLarvabiologysea urchin development gadolinium teratogenesis skeletogenesis calcium.EcologyEmbryogenesisbiology.organism_classificationCell biologyFibroblast Growth Factors030104 developmental biologychemistryLarvaParacentrotusCalciumGene expressionWater Pollutants ChemicalBiomineralization
researchProduct

Temperature and pH Dependence XAFS Study of Gd(DOTA)(-) and Gd(DTPA)(2)(-) Complexes: Solid State and Solution Structures.

1998

We present an X-ray absorption spectroscopy study of the local structures of Gd(DTPA)(2)(-) and Gd(DOTA)(-) complexes in the crystalline state (at room and low temperatures) and in aqueous solutions exhibiting various pH values (0.15-7) at different temperatures (25-90 degrees C). Using X-ray absorption fine structure (XAFS) analysis procedures and ab initio multiple scattering calculations of XAFS spectra at the Gd L(3) edge, we reconstructed the Gd(3+) local environment, and compared it with existing structural models. From neutral pH to a value of 1.5, we found that the local environment and complex dynamics around the gadolinium ions were conserved up to 4.5 Å, and the structure agreed …

Absorption spectroscopyGadoliniumAb initiochemistry.chemical_elementX-ray absorption fine structureInorganic ChemistryCrystallographychemistry.chemical_compoundchemistryDOTAMoleculeCarboxylatePhysical and Theoretical ChemistryAbsorption (chemistry)Inorganic chemistry
researchProduct

XAFS study of gadolinium and samarium bisporphyrinate complexes.

2001

The comparative X-ray absorption spectroscopy study of gadolinium and samarium bisporphyrinate complexes represented by the formulas Gd(III)H(oep)(tpp), Gd(III)(oep)(2), Gd(III)H(tpp)(2) and Sm(III)H(oep)(tpp), Sm(III)(oep)(2), Sm(III)H(tpp)(2) is reported. The XAFS spectra are recorded on the LURE-DCI storage ring (Orsay, France) in transmission mode on the microcrystalline samples at the Gd and Sm L(3) edges. The local environment for Ln(3+) ions has been reconstructed applying one-shell and two-shell XAFS analysis procedures. The protonated and nonprotonated bisporphyrinate complexes present different XAFS features. After our analysis on the title derivatives, the gadolinium ion (at 80 K…

Absorption spectroscopyGadoliniumInorganic chemistrychemistry.chemical_elementProtonationNitrogenSpectral lineIonX-ray absorption fine structureInorganic ChemistrySamariumCrystallographychemistryPhysical and Theoretical ChemistryInorganic chemistry
researchProduct

Perfusion MRI in normal and abnormal pituitary gland. A preliminary study.

1997

Perfusion MRI (magnetic resonance imaging) of the pituitary gland was performed in 20 healthy volunteers and 63 patients with various lesions involving the pituitary gland. All patients underwent sequential contrast-enhanced MRI using spoiled gradient recalled sequences with high temporal resolution (7 seconds). Four pituitary areas (pituitary stalk, posterior lobe, postero-superior, and antero-inferior adenohypophysis) were tested with a selected region of interest. Maximal contrast percentual variation was calculated. The timing of enhancement in normal patients matched perfectly with normal pituitary vascularization. Abnormal timing in pathological condition was investigated.

AdenomaGadolinium DTPAMalePituitary glandPathologymedicine.medical_specialtyPituitary diseasePituitary DiseasesContrast MediaDiagnosis DifferentialAdrenocorticotropic HormoneRegion of interestReference ValuesmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingPituitary NeoplasmsProlactinomaPathologicalPituitary stalkmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingLobemedicine.anatomical_structureRegional Blood FlowPituitary GlandFemalebusinessNuclear medicinePerfusionClinical imaging
researchProduct

Gadodiamide and gadopentetate dimeglumine in MRI versus spiral CT in the diagnosis of liver lesions.

2002

AdultAged 80 and overGadolinium DTPAMalemedicine.medical_specialtybusiness.industryGadodiamideLiver NeoplasmsContrast MediaMiddle AgedMagnetic Resonance ImagingText miningDouble-Blind MethodmedicineHumansRadiology Nuclear Medicine and imagingFemaleRadiologybusinessSpiral ctTomography Spiral Computedmedicine.drugAgedAcademic radiology
researchProduct