6533b7d1fe1ef96bd125cc9b

RESEARCH PRODUCT

Perfusion MRI in normal and abnormal pituitary gland. A preliminary study.

Roberto LagallaL. ManfrèAlberto JanniFrancesca RosatoMassimo Midiri

subject

AdenomaGadolinium DTPAMalePituitary glandPathologymedicine.medical_specialtyPituitary diseasePituitary DiseasesContrast MediaDiagnosis DifferentialAdrenocorticotropic HormoneRegion of interestReference ValuesmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingPituitary NeoplasmsProlactinomaPathologicalPituitary stalkmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingLobemedicine.anatomical_structureRegional Blood FlowPituitary GlandFemalebusinessNuclear medicinePerfusion

description

Perfusion MRI (magnetic resonance imaging) of the pituitary gland was performed in 20 healthy volunteers and 63 patients with various lesions involving the pituitary gland. All patients underwent sequential contrast-enhanced MRI using spoiled gradient recalled sequences with high temporal resolution (7 seconds). Four pituitary areas (pituitary stalk, posterior lobe, postero-superior, and antero-inferior adenohypophysis) were tested with a selected region of interest. Maximal contrast percentual variation was calculated. The timing of enhancement in normal patients matched perfectly with normal pituitary vascularization. Abnormal timing in pathological condition was investigated.

10.1016/s0899-7071(96)00087-3https://pubmed.ncbi.nlm.nih.gov/9316748