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RESEARCH PRODUCT

Determinants of short term recurrence rate of endometriosis

Parazzini FBertulessi CPasini ARosati MDi Stefano FShonauer SVicino MAguzzoli LTrossarelli GfMassobrio MBracco GAntonino PerinoMoroni SBeretta PGruppo Italiano Di Studio Endometriosi

subject

AdultInfertilitymedicine.medical_specialtyEndometriosisEndometriosisPhysical examinationCohort StudiesRecurrenceHumansMedicineProspective StudiesEndometriosiLaparoscopyProspective cohort studyPelvic examinationPregnancymedicine.diagnostic_testbusiness.industryObstetricsObstetrics and Gynecologymedicine.diseaseItalyReproductive MedicineLaparoscopyFemaleRecurrence ratebusinessCohort study

description

Objective: To analyse the frequency and the determinants of recurrence rate of clinically detectable endometriosis. Study design: Prospective cohort multicenter study. Eligible for the study were all women observed for the first time during the period January–June 1998 at the participating centres with a laparoscopically confirmed first diagnosis of endometriosis. After diagnosis, patients were treated according to standard care of each centre and desire for pregnancy. The protocol required all women to be followed up at the centre each year for 2 years with a clinical examination, an ultrasound pelvic examination and a CA125 assay, unless pregnancy occurred. Second look laparoscopy was performed on a clinical basis. Results: A total of 311 women (median age 36 years) entered the study. The two-year recurrence rate was 5.7% among cases stage I-II and 14.4% among stage III–IV (x2 1 adjusted for indication for surgery, p 30, but this finding was not statistically significant. Conclusion: The recurrence rate of clinically detectable endometriosis tends to be higher in older women with advanced stages of the disease and lower in women with infertility

https://doi.org/10.1016/j.ejogrb.2004.11.033