6533b7dbfe1ef96bd127130c
RESEARCH PRODUCT
Enzymes as Regulators of Toxic Reactions by Electrophilic Metabolites
Franz Oeschsubject
chemistry.chemical_classificationchemistry.chemical_compoundEnzymeGlutathione S-transferaseEpoxide HydratasechemistryBiochemistrybiologyBenzo(a)pyreneElectrophilebiology.proteinCarcinogendescription
Conversion of many compounds which are not electrophilically reactive as such to metabolites responsible for cytotoxic, mutagenic and/or carcinogenic effects is catalyzed by mammalian enzymes. Many reactive agents, whether metabolites or parent compounds, are also subject to inactivation by mammalian enzymes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1979-01-01 |