6533b7dbfe1ef96bd127135c

RESEARCH PRODUCT

Magnetic stimulation in the definition of eloquent cortical areas

Konrad J. Werhahn

subject

genetic structuresmusculoskeletal neural and ocular physiologymedicine.medical_treatmentStimulationmedicine.diseasebehavioral disciplines and activitiesbody regionsTranscranial magnetic stimulationEpilepsymedicine.anatomical_structurenervous systemCortex (anatomy)medicineIn patientMotor-potentialEpilepsy surgeryPsychologyNeuroscienceMotor cortex

description

Publisher Summary This chapter discusses the physiological principles of transcranial magnetic stimulation (TMS) and focus on detailing the techniques used in TMS mapping of the motor cortex relating it to the use of TMS in the presurgical assessment of patients with epilepsy. Since the main measure of TMS is the motor potential evoked in muscles, fine delineation of the functional topography of cortex is limited mainly to the primary sensorimotor cortex. In addition, TMS might be helpful to identify language dominance. The characterization of eloquent cortical areas is important in epilepsy surgery for the planning of the resection. TMS is not routinely employed for this purpose and TMS mapping is performed mainly for research purposes. This may be due to the fact that mapping of eloquent cortex is needed in patients who are studied with invasive electroencephalographic electrodes, like subdural grid electrodes that represent the “gold standard” for the delineation of cortical function through direct cortical stimulation.

https://doi.org/10.1016/s1567-4231(03)03026-0