6533b7dbfe1ef96bd1271432

RESEARCH PRODUCT

The action of iontophoretically applied acetylcholine and dopamine on single claustrum neurones in the cat.

R. CortimigliaF. InfantellinaM.t. ZagamiM. T. Salerno

subject

PharmacologyNeuronsCATSChemistryDopamineNeural InhibitionDrug applicationIontophoresisInhibitory postsynaptic potentialClaustrumAcetylcholineBasal GangliaCellular and Molecular NeuroscienceDopamineExcitatory postsynaptic potentialmedicineCatsAnimalsNeuroscienceAcetylcholinemedicine.drug

description

Abstract The effects of iontophoretically applied acetyl-choline (ACh) and dopamine (DA) on spontaneously active claustral neurones, in chloralose-anaesthetised cats, have been investigated. Acetylcholine had both facilitatory and inhibitory effects in almost the same proportions. The action of DA was prevalently inhibitory. Two types of inhibitory response to ACh and DA are described: short-lasting inhibition and long-lasting inhibition. The excitatory response always outlasted the period of drug application.

yearjournalcountryeditionlanguage
1981-09-01Neuropharmacology
10.1016/0028-3908(81)90085-xhttps://pubmed.ncbi.nlm.nih.gov/7290362