6533b7dcfe1ef96bd1271757
RESEARCH PRODUCT
A singular case of near-haploid stemline karyotype in a renal oncocytoma.
Luisa Morell-quadrenyM. Aurelia Gregori-romeroAntonio Llombart-boschsubject
MaleCancer Researchmedicine.medical_specialtyPathologyMonosomyAneuploidyBiologyHaploidyurologic and male genital diseasesGeneticsmedicineAdenoma OxyphilicHumansOncocytomaSingular caseRenal oncocytomaMolecular BiologyKidneyCytogeneticsKaryotypeAnatomyMiddle Agedmedicine.diseaseKidney Neoplasmsmedicine.anatomical_structureKaryotypingdescription
Cytogenetic analysis of a human renal oncocytoma revealed a near-haploid chromosome number of 36 with the loss of chromosomes 1, 2, 3, 6, 8, 9, 15, 17, 21, and 22. Review of the literature disclosed that this cytogenetic configuration is extremely rare in solid human tumors and that no renal oncocytomas with near-haploid stemline karyotype have been described. These results are compared with the other published cases of oncocytoma.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1996-11-01 | Cancer genetics and cytogenetics |