6533b7dcfe1ef96bd1271d25
RESEARCH PRODUCT
Functionality transfer from C8 to C9 in sesquiterpenes. Synthesis of the named Herbolide E from artemisin.
Gonzalo BlayLuz CardonaJosé R. PedroBegoña Garcíasubject
ArtemisineChemistryStereochemistryOrganic ChemistryDrug DiscoveryChemical reductionBiochemistrydescription
Abstract The key intermediate 6 was obtained in five steps from artemisin (1). The spectroscopic characteristics of the synthetic product 7a reveal that the proposed structure for the natural herbolide E must be revised.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-09-01 | Tetrahedron Letters |