Search results for "Artemisine"

showing 4 items of 4 documents

Functionality transfer from C8 to C9 in sesquiterpenes. Synthesis of the named Herbolide E from artemisin.

1992

Abstract The key intermediate 6 was obtained in five steps from artemisin (1). The spectroscopic characteristics of the synthetic product 7a reveal that the proposed structure for the natural herbolide E must be revised.

ArtemisineChemistryStereochemistryOrganic ChemistryDrug DiscoveryChemical reductionBiochemistryTetrahedron Letters
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Synthesis of various natural 8,12-elemanolides from artemisin

1989

Abstract This paper describes the chemical transformations of artemisin into various natural 8,12-elemanolides.

chemistry.chemical_classificationArtemisineBicyclic moleculeChemistryOrganic ChemistryDrug DiscoveryOrganic chemistryEpimerBiochemistryBond cleavageLactoneTetrahedron
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13C NMR spectra of eudesmanolides I—eudesman-12,6-olides

1987

The 13C NMR spectra of 26 eudesmanolides of natural and synthetic origin have been measured, including the naturally occurring sesquiterpene lactones artemisin, torrentin, rothin-A and rothin-B and several semi-synthetic eudesman-12,6-olides obtained from artemisin. The chemical shift values of the different compounds are compared and the effects of the substituents are discussed.

chemistry.chemical_classificationGeneral ChemistryNuclear magnetic resonance spectroscopyCarbon-13 NMRSesquiterpeneSpectral linechemistry.chemical_compoundArtemisinechemistryProton NMROrganic chemistryChemical solutionGeneral Materials ScienceLactoneMagnetic Resonance in Chemistry
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Transformation of artemisin into artapshin and 8α-hydroxy-11β,13-dihydrobalchanin

1987

Abstract Partial syntheses of the sesquiterpene lactones artapshin ( 1 ) and 8α-hydroxy-11β, 13-dihydrobalchanin ( 2 ) from artemisin ( 3 ) are described.

chemistry.chemical_classificationStereochemistryOrganic ChemistryDiolEpoxideAlcoholSesquiterpeneBiochemistrychemistry.chemical_compoundTransformation (genetics)ArtemisinechemistryDrug DiscoveryOrganic chemistryLactoneTetrahedron
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