6533b85ffe1ef96bd12c1aac

RESEARCH PRODUCT

Transformation of artemisin into artapshin and 8α-hydroxy-11β,13-dihydrobalchanin

Begoña GarcíaJosé R. PedroIsabel Fernández

subject

chemistry.chemical_classificationStereochemistryOrganic ChemistryDiolEpoxideAlcoholSesquiterpeneBiochemistrychemistry.chemical_compoundTransformation (genetics)ArtemisinechemistryDrug DiscoveryOrganic chemistryLactone

description

Abstract Partial syntheses of the sesquiterpene lactones artapshin ( 1 ) and 8α-hydroxy-11β, 13-dihydrobalchanin ( 2 ) from artemisin ( 3 ) are described.

https://doi.org/10.1016/s0040-4020(01)90016-x