6533b7dcfe1ef96bd1271ee1

RESEARCH PRODUCT

Reduced regional systolic function evolved compacted segments in noncompaction

Indovina GSalvatore NovoLoredana SuteraGiovanni FazioNovo GiuseppinaFilippo FerraraGabriele Di GesaroLuciana D'angeloMonica Lunetta

subject

education.field_of_studymedicine.medical_specialtymedicine.diagnostic_testbusiness.industryPopulationSystolic functionScintigraphymedicine.diseaseUncorrelatedmedicine.anatomical_structure2d echocardiographysystolic function noncompactionFibrosisVentricleInternal medicinemedicineCardiologyWall motionCardiology and Cardiovascular Medicineeducationbusiness

description

Abstract In a recent report about noncompaction Nemes et al. reported that systolic left ventricular (LV) dysfunction assessed using the wall motion score during 2D echocardiography in noncompaction is not confined to noncompacted LV segments. These results confirmed some published reports of our group. Recently we analyzed a population of 238 patients affected by noncompaction, and demonstrated that the number of noncompacted segment is uncorrelated with the degree of systolic dysfunction. It is an attractive hypothesis that the systolic dysfunction could be depend on the fibrosis of the left ventricle, itself a consequence of microcirculatory dysfunction, which has been confirmed by reports that describe microvascular dysfunction using myocardial scintigraphy.

http://hdl.handle.net/10447/53710