6533b7dcfe1ef96bd1271f3a

RESEARCH PRODUCT

Lead-Related Infective Endocarditis in Latvia: A Single Centre Experience

Janis AnsabergsPeteris StradinsAija MacaMaris BlumbergsGinta KamzolaNikolajs NesterovicsAndrejs ĒRglisAivars LejnieksMartins KalejsGeorgijs NesterovicsOskars Kalejs

subject

AdultMalemedicine.medical_specialtymedicine.drug_classAntibioticsDiseasemedicine.disease_causeArticleAntibiotic resistanceQuality of lifelead-related infective endocarditisRisk FactorsInternal medicinemedicineHumansAgedRetrospective StudiesAged 80 and overHeart Failurelcsh:R5-920cardiac implantable electronic devicesEndocarditisbusiness.industryArrhythmias CardiacGeneral Medicinecardiac device infectionProstheses and ImplantsMiddle Agedmedicine.diseaseLatviaLRIE mortalityLeadStaphylococcus aureusEchocardiographyInfective endocarditisHeart failureCIED complicationFemalelead-related infective endocarditis; cardiac implantable electronic devices; cardiac device infection; CIED complication; LRIE mortalityCoagulasebusinesslcsh:Medicine (General)

description

Background and Objectives: Over the last five decades cardiac implantable electronic devices (CIED) have become established as the mainstay for the treatment of permanent bradycardias, chronic heart failure and dangerous heart rhythm disturbances. These devices improve survival and quality of life in many patients. However, infections associated with CIED implantation, particularly lead-related infective endocarditis (LRIE), can offset all benefits and make more harm than good for the patient. To date, there are no other studies in Latvia, addressing patients with lead-related infective endocarditis. The objective of this study was to identify the most common pathogens associated with LRIE and their antimicrobial resistance and to identify possible risk factors of patients who present with LRIE. Materials and Methods: The study was performed retrospectively at Pauls Stradins Clinical University Hospital (PSCUH). The study included patients who were referred to PSCUH due to LRIE for lead extraction. Patients were identified from procedural journals. Information about isolated microorganisms, patient comorbidities and visual diagnostics data was taken from patient records. Results: Forty-nine patients with CIED related infective endocarditis were included in the study, 34 (69.4%) were male, median age of all patients was 65.0 (50.5&ndash

yearjournalcountryeditionlanguage
2019-09-03Medicina
10.3390/medicina55090566http://europepmc.org/articles/PMC6780120