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RESEARCH PRODUCT
Langerhans cell histiocytosis: Current concepts in dentistry and case report
Amaury Pozos-guillénFrancisco Alejo-gonzálezEfraín Ramos-gutiérrezSocorro Ruiz-rodríguezJosé-arturo Garrocho-rangelsubject
Pathologymedicine.medical_specialtyCase ReportOdontologíaDisease03 medical and health sciences0302 clinical medicineLangerhans cell histiocytosisEosinophilic granulomamedicineGeneral DentistryCraniofacial boneOral Medicine and Pathologybusiness.industryClinical course030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludSkullHistiocytosismedicine.anatomical_structure030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASEtiologybusinessdescription
Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their marrow precursors, resulting in localized, solitary or multiple destructive lesions. These lesions are most commonly eosinophilic granuloma, which are found in craniofacial bone structures such as the skull and mandible, skin and other organs. In children, the disease has a variable initial presentation, and the clinical course, prognosis and survival are unpredictable. The aims of this report were to present an LCH case in a girl aged 2 years, 8 months and her clinicopathological features, to describe the bucodental management provided, and to discuss special dental considerations of this disease
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 | Journal of Clinical and Experimental Dentistry |