6533b7dcfe1ef96bd127209f

RESEARCH PRODUCT

Complementation among developmental mutants in Aspergillus nidulans.

subject

description

In heterokaryons between pairs of aconidial mutants of Aspergillus nidulans one of the component strains usually shows a striking prevalance in the contribution to the conidial crop. By assuming that the prevailing strain is blocked earlier and the succumbent one later in the process of differentiation, a series of mutations can be arranged in a consistent order. Some mutant strains do not fit the scheme exactly but show a general tendency to be succumbent to “early” mutants and prevalent over the “late” ones. A criterion for arraying genes involved in differentiation according to the order of their physiological action is proposed.