6533b7dcfe1ef96bd1272141

RESEARCH PRODUCT

Surgical therapy of recurrent vulvar cancer.

Eric SteinerW. WeikelPaul-georg KnapsteinMarkus SchmidtHeinz Koelbl

subject

Adultmedicine.medical_specialtyReconstructive surgeryDatabases FactualVulvaTumor StatusGynecologic Surgical ProceduresmedicineHumansVulvar DiseasesAgedRecurrent Vulvar CarcinomaVulvar neoplasmAged 80 and overWound HealingVulvar Neoplasmsbusiness.industryCarcinomaObstetrics and GynecologyMiddle AgedPlastic Surgery Proceduresmedicine.diseasePrognosisPrimary tumorSurvival AnalysisSurgeryPlastic surgerymedicine.anatomical_structureFemaleNeoplasm Recurrence Localbusiness

description

Objective The success of various surgical interventions in 201 cases with recurrent vulvar carcinoma was examined in the light of patients' pretreatment, surgical therapy, plastic reconstruction, and postoperative disease course. Study design A databank of standardized clinical data was analyzed using statistical procedures. Results Therapy was selected on an individual basis according to tumor status. Recurrence at a site distant from the primary tumor, particularly in the inguinal region, indicated a markedly unfavorable prognosis. In contrast, tumors recurring locally did not exhibit any significant differences. Plastic surgery reconstruction led to improvements with respect to operability, wound healing, and survival. Conclusion Individualized reconstructive surgery of the vulva leads to good results in patients with recurrent vulvar cancer. To an even greater extent than is the case for primary therapy, plastic surgery enlarges the spectrum of feasible surgical alternatives so that a more favorable oncological outcome and excellent cosmetic results may be expected.

10.1016/j.ajog.2006.03.049https://pubmed.ncbi.nlm.nih.gov/16681985