6533b7dcfe1ef96bd127219b

RESEARCH PRODUCT

Acetogenins from Annonaceae: Recent Progress in Isolation, Synthesis and Mechanisms of Action

Bruno FigadèreDiego CortesErnesto EstornellM. C. Zafra‐poloAlmudena BermejoIsabel BarrachinaIsabel Barrachina

subject

AcetogeninsIsolation (health care)StereochemistryAnnonacinAnnonaceaeComputational biologyBiochemistryLactoneschemistry.chemical_compoundDrug DiscoverymedicineMolecular StructureTraditional medicinebiologyChemistryOrganic ChemistryGeneral Medicinebiology.organism_classificationAntineoplastic Agents PhytogenicAction (philosophy)Mechanism of actionAnnonaceaeAcetogeninFatty AlcoholsAnnonaceous Acetogeninsmedicine.symptomBullatacin

description

Covering: the literature from 1998 to 2004 The aim of the present review is to summarise the knowledge about newly isolated acetogenins (ACGs) in the last six years. It will also report the total syntheses that have allowed either the confirmation or the revision of some structures, together with the biological activities and mechanism of action of such interesting natural products. In fact, of the 417 isolated compounds reviewed, over 176 have been added during the period from 1998 to 2004.

https://doi.org/10.1002/chin.200531238