6533b7dcfe1ef96bd1272507
RESEARCH PRODUCT
A radical signal activates the epigenetic regulation of longevity
Mario Giuseppe MirisolaVd Longosubject
Settore BIO/13 - Biologia Applicataepigenetic stress resistance hormesisdescription
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) have now connected stress, epigenetic changes, and aging in yeast by showing that mitochondria-derived reactive oxygen species modulate the chromatin binding capacity of the histone demethylase Rph1p at subtelomeres, resulting in lifespan extension.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 |