6533b7dcfe1ef96bd12729ab

RESEARCH PRODUCT

Oral Surgical Management of Bone and Soft Tissues in MRONJ Treatment: A Decisional Tree.

Antonia MarcianòErasmo RubinoGiacomo OteriRodolfo MauceriMatteo Peditto

subject

medicine.medical_specialtyReconstructive surgerymedicine.medical_treatmentMRONJ surgical treatmentGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciences0302 clinical medicineSymptom reliefQuality of lifemedicineReconstructive surgery.Stage (cooking)lcsh:ScienceEcology Evolution Behavior and SystematicsSurgical approachDebridementbusiness.industryMRONJ managementPaleontologySoft tissueRetrospective cohort study030206 dentistryreconstructive surgerySurgerySpace and Planetary Science030220 oncology & carcinogenesislcsh:Qbusinessoral flaporal flaps

description

Background: The aim of the present work was to analyze a 10-year retrospective series of surgically treated medication-related osteonecrosis of the jaws (MRONJ) cases, reporting the clinical outcome and success rate for each adopted procedure in order to draw a treatment algorithm that is able to standardize clinical decision making and maximize the success of oral surgical treatment of MRONJ. Methods: Different surgical approaches were categorized taking into consideration two variables a) hard tissue management (defined as debridement, saucerization or marginal resective surgery of maxillary necrotic bone) and b) soft tissue management (defined as type of flap design and related modality of wound-healing). Results: For the retrospective cohort study, 103 MRONJ patients were enrolled and a total of 128 surgical procedures were performed. The role of radical-intended surgery using local flaps in MRONJ treatment was investigated, as well as palliative treatments. All stage I&ndash

yearjournalcountryeditionlanguage
2020-06-29Life (Basel, Switzerland)
10.3390/life10070099https://pubmed.ncbi.nlm.nih.gov/32610675