6533b7dcfe1ef96bd1272a67

RESEARCH PRODUCT

A case of naturally evolving gout in an elderly man

Giuseppe SergiEnzo ManzatoNicola VeroneseValter GiantinMarco MoseleFrancesco Bolzetta

subject

Malemusculoskeletal diseasesAgingPediatricsmedicine.medical_specialtyHealth (social science)GoutAllopurinolOrgan functionDiseaseTophaceous gout in elderly Renal failure Sepsis HyperuricemiaMethylprednisoloneSeverity of Illness IndexGout SuppressantsTophaceous goutSepsisFatal OutcomeQuality of lifeRenal DialysisChronic goutSepsismedicineHumansHyperuricemiaMobility LimitationAgedbusiness.industryAcute Kidney Injurymedicine.diseaseArthralgiaAnti-Bacterial AgentsGoutSurgeryChronic DiseaseQuality of LifeDrug Therapy CombinationGeriatrics and GerontologyColchicineRespiratory InsufficiencybusinessGerontology

description

Gout is a common disorder in adults that can lead to severe organ decline, disability and impaired quality of life due to the formation of periarticular tophi. We report a case of massive tophaceous gout in a 78-year-old man with a 16-year-long history of untreated disease. The patient gradually became disabled, his renal function deteriorated, and he finally died of sepsis. Our case demonstrates that chronic gout not only affects the joints, but is also associated with organ function decline and can, even nowadays, lead to death. © 2011 Elsevier Ireland Ltd.

10.1016/j.archger.2011.09.002http://hdl.handle.net/11577/2490026