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RESEARCH PRODUCT
Liver stiffness measurement by transient elastography predicts early recovery from acute hepatitis
Fabrizio BronteAntonio CraxìVincenza CalvarusoRaffaele BrunoGiovanni SquadritoMassimo PuotiVito Di MarcoAlessandra IacòL. BiasiGiuliana AmaddeoK. PrestiniPaolo Sacchisubject
Pathologymedicine.medical_specialtyNecrosisbusiness.industryGastroenterologyEarly recoveryContext (language use)Gastroenterologyliver stiffnessLiver stiffnessInternal medicineAcute Disease; Adult; Elasticity Imaging Techniques; Female; Hepatitis Viral Human; Humans; Male; Middle Aged; PrognosisEtiologymedicinemedicine.symptomTransient elastographyHepatic fibrosisbusinessAcute hepatitisdescription
We read with interest the lead article by Castera and Pinzani,1 particularly the comment regarding the role of transient elastography (TE) in the context of acute hepatitis (AH). The assumption that liver stiffness is determined exclusively by hepatic fibrosis has been challenged by evidence that patients with AH can have high values of liver stiffness measurement (LSM) by TE.2 AH is a suitable model for studying the kinetics of LSM, since inflammation and necrosis increase rapidly and sometimes massively, but may revert with equal speed. We evaluated 92 consecutive patients (mean age 41.8±16.3 years, 71.7% males) with symptomatic AH to assess how LSM was influenced by aetiology, and whether LSM kinetics correlated with the clinical course of AH. Twelve patients (13%) had …
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-12-09 |