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RESEARCH PRODUCT

Psoriasis and Its Impact on In-Hospital Outcome in Patients Hospitalized with Acute Kidney Injury

Kerstin SteinbrinkSusanne KarbachThomas MünzelLukas HobohmJohannes WildPhilip WenzelKarsten KellerKarsten Keller

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trendsmedicine.medical_specialtymedicine.medical_treatmentdermatoepidemiologylcsh:MedicineDisease030204 cardiovascular system & hematologyurologic and male genital diseasesArticle030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineAKIInternal medicinePsoriasismedicineIn patientMyocardial infarctionStrokeDialysisbusiness.industrylcsh:RAcute kidney injuryGeneral Medicinepsoriasismedicine.diseasemortalityConcomitantbusiness

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Background: Psoriasis is a chronic inflammatory disease which affects the body far beyond the skin. Whereas there is solid evidence that chronic skin inflammation in psoriasis drives cardiovascular disease, the impact on renal impairment and acute kidney injury (AKI) is still unclear. We aimed to analyze the impact of psoriasis on the in-hospital outcome of patients hospitalized with AKI. Methods: In this retrospective database study, we investigated data on characteristics, comorbidities, and in-hospital outcomes for all hospitalized patients with AKI stratified for concomitant psoriasis, which were collected by the Federal Office of Statistics in Germany between 2005 and 2016. Results: Among the 3,162,449 patients treated for AKI in German hospitals between 2005 and 2016, 11,985 patients (0.4%) additionally suffered from psoriasis. While the annual number of AKI patients with psoriasis increased significantly from 485 cases (4.0%) in 2005 to 1902 (15.9%) in 2016 (p &lt

yearjournalcountryeditionlanguage
2020-09-17Journal of Clinical Medicine
10.3390/jcm9093004http://dx.doi.org/10.3390/jcm9093004