6533b7dcfe1ef96bd1272b62
RESEARCH PRODUCT
Acrosin, the peculiar sperm-specific serine protease.
Uwe KlemmWerner Müller-esterlWolfgang Engelsubject
MaleProteasesMolecular Sequence DataSemenSerine03 medical and health sciencesGeneticsAnimalsHumansAmino Acid SequenceGenetics (clinical)030304 developmental biologyPREPROACROSINchemistry.chemical_classificationSerine protease0303 health sciencesAcrosinbiology030302 biochemistry & molecular biologyAcrosinSpermSpermatozoa3. Good healthEnzymechemistryBiochemistrybiology.proteinSequence Alignmentdescription
The sperm enzyme acrosin has long been known as one of the key enzymes in the mammalian fertilization process. Elucidation of primary structures of preproacrosin from various species have allowed a deeper insight into the structural organization and the complex evolution of the sperm proteinase acrosin. In addition to the typical elements of serine proteases, the acrosin molecule possesses one novel domain that might convey DNA-binding properties.
year | journal | country | edition | language |
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1991-10-01 | Human genetics |