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RESEARCH PRODUCT
Five Challenges in the Field of Viral Diversity and Evolution
Jaime IranzoSiobain DuffyDhanasekaran VijaykrishnaRafael SanjuánAlexander T. CiotaChristopher J. R. IllingworthSelma Gago-zachertGonzalo MoratorioGonzalo MoratorioJemma L. GeogheganMark P. Zwartsubject
0303 health sciencesViral metagenomicsExperimental evolutionField (physics)030306 microbiologymedia_common.quotation_subjectvirusesGeneral MedicineBiology3. Good health03 medical and health sciencesEvolutionary biologyViral evolutioninternationalPlan_S-Compliant_OA030304 developmental biologyDiversity (politics)media_commondescription
Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, more thoroughly characterizing the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to more efficiently use viral diversity and evolution for biotechnological purposes.
year | journal | country | edition | language |
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2021-04-29 | Frontiers in Virology |