6533b7dcfe1ef96bd1273218

RESEARCH PRODUCT

ChemInform Abstract: Synthetic Approaches to Antiinflammatory Macrolactones of the Oxacyclododecindione Type.

Gerhard ErkelJohannes TauberMarkus RohrTill OpatzKristina Rudolph

subject

chemistry.chemical_classificationDouble bondchemistryStereochemistryIntramolecular forceSalt metathesis reactionOxacyclododecindioneAlkyneGeneral MedicineIsomerization

description

A variety of attempts to synthesize oxacyclododecindione macrolactones through carbonylative ring-closure, intramolecular alkyne hydroacyalation, and Ru-catalyzed double bond isomerization fails.

https://doi.org/10.1002/chin.201539167