6533b7dcfe1ef96bd12732ef

RESEARCH PRODUCT

Solid State Structures of Amide-Substituted 8-Hydroxyquinoline Derivatives

Elina WegeliusKaren WittMarkus AlbrechtKari Rissanen

subject

chemistry.chemical_classificationHydrogenHydrogen bondOrganic ChemistryLow-barrier hydrogen bondSolid-statechemistry.chemical_element8-HydroxyquinolinePolymerBiochemistrySolid state structurechemistry.chemical_compoundchemistryAmideDrug DiscoveryPolymer chemistryOrganic chemistry

description

Abstract The amide substituted 8-hydroxyquinoline derivatives 3 and 4 form, in the solid state, hydrogen bonded polymers. Polymeric 3 adopts a helical conformation while 4 forms a double-stranded ladder-type structure.

https://doi.org/10.1016/s0040-4020(99)01057-1