6533b7dcfe1ef96bd1273378

RESEARCH PRODUCT

Neurosurgical Odyssey: Case of Anaplastic Meningiomatosis.

Giovanni GrassoAntonella GiugnoDomenico Gerardo IacopinoRosario MaugeriFrancesca Graziano

subject

Meningiomatosismedicine.medical_specialtybusiness.industrySettore MED/27 - Neurochirurgiamedicine.diseaseMeningioma03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesismedicineMeningeal NeoplasmsHumansSurgeryNeurology (clinical)RadiologybusinessMeningioma WHO SurgeryMeningioma030217 neurology & neurosurgery

description

According to the World Health Organization grading, meningiomas are classified as grade I (benign), grade II (atypical), and grade III (anaplastic). Most of them (81%) are benign, 15% are atypical, and 4% are anaplastic. Metastasis is a rare event in meningiomas, occurring in <1% of cases. In most types of tumors, distant metastasis is an incontrovertible indication of malignancy. This is not so clearly the case with meningiomas, mostly in the multiple localization of these tumors, known as meningiomatosis. Here we would like to share our experience with a unique case of an atypical meningioma, which evolved in an anaplastic multiple meningiomatosis, invading the brain and associated with a subcutaneous metastasis.

yearjournalcountryeditionlanguage
2017-05-18World neurosurgery
10.1016/j.wneu.2017.05.120https://pubmed.ncbi.nlm.nih.gov/28143726