Papaverine decreases the efflux of42K in guinea-pig atrial heart muscle

6533b7dcfe1ef96bd1273405

RESEARCH PRODUCT

Papaverine decreases the efflux of42K in guinea-pig atrial heart muscle

subject

Male medicine.medical_specialty Time Factors Potassium Guinea Pigs Pharmacology toxicology Potassium Radioisotopes Action Potentials chemistry.chemical_element In Vitro Techniques Guinea pig Papaverine Internal medicine medicine Animals Pharmacology Papaverine Chemistry Myocardium General Medicine Myocardial Contraction Resting potential Endocrinology Potassium Female Efflux medicine.drug

description

The effects of papaverine on resting potential and efflux of42K were investigated in guinea-pig left atria. Papaverine significantly reduced the potassium efflux in beating preparations. In resting preparations, the efflux of potassium was only slightly affected. However, the resting potential was significantly reduced by papaverine by about 5 mV.

year	journal	country	edition	language
1980-06-01	Naunyn-Schmiedeberg's Archives of Pharmacology

https://doi.org/10.1007/bf00569728

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