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RESEARCH PRODUCT
Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
Nikolaos KatsoulasAlexandra SklavounouAndreas C. LazarisEleni-marina KalogirouKonstantinos I. Tosiossubject
musculoskeletal diseasesmedicine.medical_specialtyCase ReportOdontologíaDisease030207 dermatology & venereal diseases03 medical and health sciencesPsoriatic arthritis0302 clinical medicineTonguemedicineOral ulcersskin and connective tissue diseasesAdverse effectGeneral DentistryLeflunomide030203 arthritis & rheumatologyOral Medicine and Pathologybusiness.industry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludDermatology3. Good healthSurgerymedicine.anatomical_structureAdverse drug eventRheumatoid arthritisUNESCO::CIENCIAS MÉDICASbusinessmedicine.drugdescription
Leflunomide is a member of the disease modifying anti-rheumatic drugs group used as a treatment modality in active rheumatoid and psoriatic arthritis. “Oral ulcers” are reported in 3-5% of leflunomide medicated rheumatoid arthritis patients with adverse events, but they are not described in detail in the literature. We present a case of an ulcer in the tongue of a rheumatoid arthritis patient managed with leflunomide and contemplate on its pathogenesis. Key words:Leflunomide, oral ulcer, DHODH.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-02-01 | Journal of Clinical and Experimental Dentistry |