6533b7ddfe1ef96bd1273d89

RESEARCH PRODUCT

Formation of basement membrane in extracapillary proliferates in rapidly progressive glomerulonephritis

Helmut E. GabbertW. Thoenes

subject

Basement membranePathologymedicine.medical_specialtyurogenital systemChemistryKidney Glomerulusfood and beveragesGlomerulonephritisAnatomyEndoplasmic Reticulumurologic and male genital diseasesmedicine.diseaseBasement Membranefemale genital diseases and pregnancy complicationsPathology and Forensic MedicineGlomerulonephritismedicine.anatomical_structuremedicineHumansRapidly progressive glomerulonephritisReticulum

description

In the extracapillary proliferations (crescents) of the glomeruli in glomerulonephritis, basement membranes appear and in addition "secretory bodies" are formed in the cisternae of the rough endoplasmatic reticulum. The findings permit the conclusion that proliferated visceral epithelial cells are involved in the crescent formation to a greater extent than previously assumed.

https://doi.org/10.1007/bf02889439