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RESEARCH PRODUCT

MOESM2 of The distributions of protein coding genes within chromatin domains in relation to human disease

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Additional file 2: Figure S2. Distribution of the distances from the TSS of the genes to their closest TAD borders depending on the gene association with disease. The TAD border is represented with a vertical black line. Blue and salmon color represent genes associated and not with disease, respectively. If the TSS is within a TAD a negative distance is calculated, otherwise the distance is positive. a. HK genes. b. non-HK genes. Insets: The densities for the same data is shown. Genes not associated with disease have higher preference for TAD borders but this is only significant for non-HK genes (p-value = 9 × 10−11, Wilcoxon rank test).