6533b7ddfe1ef96bd1273fe0

RESEARCH PRODUCT

Laparoscopic Microwave Thermal Ablation for the Treatment of Hepatocellular Carcinoma in Chronic Hepatic Patients

Alessandro TropeaLaura LomaglioMarco BarbaraFabrizio Di FrancescoDuilio PaganoPasquale BonsignoreSalvatore GruttadauriaSalvatore GruttadauriaSergio Calamia

subject

Liver CirrhosisMaleLaparoscopic surgerymedicine.medical_specialtyCarcinoma Hepatocellularmedicine.medical_treatmentHepatitis C virusmedicine.disease_causeGastroenterologyLiver diseasePregnancymicrowave thermoablationInterquartile rangeInternal medicinemedicineHepatectomyHumansRisk factorMicrowavesAgedmedicine.diagnostic_testbusiness.industryLiver NeoplasmsHyperthermia Inducedhepatocellular carcinomaHepatitis C ChronicMiddle Agedmedicine.diseaselaparoscopic surgerySurgeryHepatocellular carcinomaCatheter AblationFemaleLaparoscopySurgeryLiver function testsbusinessBody mass index

description

Background: Laparoscopic microwave thermal ablation (LMWTA) is a well-established alternative treatment to liver resection for treatment of liver tumors. The aim of this study was to describe our experience in LMWTA for hepatocellular carcinoma (HCC) in chronic hepatic patients. Materials and Methods: A study group of 61 consecutive HCC patients treated with LMWTA from January, 2013 to May, 2020 were considered for this study. Patient characteristics, liver function test, operational characteristics, and complications were recorded. Results: Of the 61 patients who underwent LMWTA, median age was 64 (interquartile range [IQR]: 58-71) years, mean body mass index was 26.2 (IQR: 23.2-29.4); 44 patients (72%) presented with an hepatitis C virus etiology, 46 (75%) were Child-Pugh Class A, median model for end-stage liver disease (MELD) score was 8.0 (IQR: 7.0-9.4). Viral infection was confirmed to be the most important risk factor in determining progressive cirrhotic evolution with HCC expression. Conclusions: LMWTA is a safe alternative treatment to traditional surgery, and can be combined with surgery.

yearjournalcountryeditionlanguage
2020-01-01Journal of Laparoendoscopic & Advanced Surgical Techniques
https://doi.org/10.1089/lap.2020.0513