6533b7ddfe1ef96bd1273ff3

RESEARCH PRODUCT

Evaluation of automated hematologic VCS parameters in severe sepsis and septic shock: a case-control study.

Santi Maurizio RaineriA Di BenedettoAndrea CortegianiCeleste SarnoAntonino GiarratanoG VirgaL MarinoR Chiaramonte

subject

medicine.medical_specialtybusiness.industrySeptic shockCell volumeSevere SepsiCase-control studySettore MED/41 - AnestesiologiaCritical Care and Intensive Care Medicinemedicine.diseaseSepsisSeptic ShockHematology analyzerInternal medicinePoster PresentationmedicineCardiologyVCSIntensive care medicinebusinessSevere sepsis

description

A cheap and quick hematologic diagnostic parameter for detection of sepsis would have both economic and therapeutic benefits. The Coulter LH series hematology analyzer uses the VCS technology (Volume, Conductivity, Laser Scatter) providing information about cell volume, size, internal structure, and surface morphology. Many authors analyzed the clinical usefulness of VCS parameters in reactive neutrophils for detection of sepsis. An increase in mean cell volume and a decrease in mean light scatter in septic patients have been described. Our aim is to verify the correlation between VCS parameters and sepsis.

http://europepmc.org/abstract/PMC/PMC2934270