6533b7ddfe1ef96bd12740d2
RESEARCH PRODUCT
Substituent effect on the redox potential of substituted (aryl)(2-nitrobenzo[ b ]thiophen-3-yl)amines
Domenica TonelliLiliana LamartinaBarbara CosimelliDomenico SpinelliRenato SeeberM. C. SarvaFrancesca Costanzosubject
ChemistryArylOrganic ChemistrySubstituentDropping mercury electrodeBiochemistryRedoxMedicinal chemistrychemistry.chemical_compoundorganic electrochemistry substituents effect on thermodynamics redox processesDrug DiscoveryElectronic effectOrganic chemistryCyclic voltammetrydescription
Abstract The electronic effect of some meta- or para-substituents on the reduction of the title compounds has been investigated. The reversible reduction potential values of these compounds have been evaluated by cyclic voltammetry at a mercury electrode in 0.1 M tetraethylammoniumtetrafluoroborate, dimethylsulfoxide solutions. The substituent effect depends on both its nature and its position. The reduction potential values of the derivatives studied have been correlated with the Hammett substituent constants.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-02-01 | Tetrahedron |