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RESEARCH PRODUCT

Zur H�ufigkeit der Serumprotein-Polymorphismen Hp, Gc, Gm, InV und Lp in Griechenland

C. YannissisH. Walter

subject

Geneticsmedicine.medical_specialtyEndocrinologyPolymorphism (computer science)Internal medicineGeneticsmedicineSerum proteinAlleleGreek populationBiologyGenetics (clinical)

description

The authors report the frequencies of Hp-, Gc-, Gm-, InV-, and Lp-phenotypes and alleles in a Greek sample of 218 unrelated adult males and females. The following gene-frequencies were obtained: Hp1=.2850, Hp2=.7150; Gc1=.7590, Gc2=.2410; Gm1=.1555, Gm1,2=.1015, Gm12=.7430. The phenotype InV (1) was found to be 14.6%. Lp (ax)-typing showed 17.0% strong positive individuals, 9.7% weak positive ones, and 73.3% negatives. According to Speiser and Pausch (1965) this may be interpreted as the following phenotypes distribution: Lp (a+x+)=17.0%, Lp(a+x-)=9.7%, and Lp(a-x-)=73.3%. Our data differ somewhat from data obtained by other authors, which seems to indicate heterogeneity in the distribution of at least Hp- and Gm-phenotypes within the Greek population. This is project to further research.

https://doi.org/10.1007/bf00291257