6533b7ddfe1ef96bd1274a32
RESEARCH PRODUCT
Gold(I)-catalysed cascade reactions in the synthesis of 2,3-fused indole derivatives.
Alejandra Rodríguez-gimenoCarmen Ramírez De ArellanoMercedes Medio-simónAna GimenoAna B. CuencaGregorio Asensiosubject
Indole testIndolesChemistryMetals and AlloysGeneral ChemistryCombinatorial chemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCatalysisX-Ray DiffractionCascadeMaterials ChemistryCeramics and CompositesOrganic chemistryGolddescription
A gold(I)-catalysed hydroaminative/arylative cascade for the efficient synthesis of a variety of indole-fused skeletons has been developed. Factors controlling the catalyst loading required in these transformations involving 1,3-unsubstituted indole intermediates have been revealed, allowing isolation of an unprecedented 1,3-dimetallated 3H-indole gold complex characterized by X-ray diffraction.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-07-04 | Chemical communications (Cambridge, England) |