6533b7ddfe1ef96bd127515b
RESEARCH PRODUCT
Prise en charge au long cours par les anti-agrégants plaquettaires oraux après un syndrome coronaire aigu
Luc LorgisIsabelle L’huillierC. NguyenP. ObbeeYves CottinF. SchaadJean Claude BeerA.-c. LagrostMarianne ZellerPhilippe Buffetsubject
medicine.medical_specialtyAcute coronary syndromeAspirinbusiness.industryDeveloping countryEarly deathDiseasemedicine.diseaseClopidogrelSurgeryMedicineMyocardial infarctionCardiology and Cardiovascular MedicinebusinessIntensive care medicineTherapeutic strategymedicine.drugdescription
Cardiovascular disease is the primary cause of early death and morbidity in the industrialized world and is becoming a growing problem in many developing countries. Coagulation inhibitors play a major role in the management of the acute phase of ACS whether in association with reperfusion strategies or not. Currently, and in accordance with the results of major randomised studies, for medium and long-term management, the association of Clopidogrel and aspirin is the treatment of choice. However, despite the recognised benefits of this therapeutic strategy and above all the recommendations of learned societies, which have placed this bi-therapy in class I, according to national and international registries it is still underused. Moreover, all of these registries have confirmed, in the real world, the negative impact of not prescribing this antiplatelet therapy on morbidity and mortality after both ST and non-ST elevation acute coronary syndrome. which shows the difficulty of applying to everyday clinical practice the results of major randomised cohorts.
year | journal | country | edition | language |
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2007-06-01 | Annales de Cardiologie et d'Angéiologie |