6533b7ddfe1ef96bd1275301
RESEARCH PRODUCT
Novel Domino Oxidative Coupling: C−C Bond Formation Sequence to Highly Functionalized Dibenzo[a,c]cycloheptenes
Kristina HackelöerGregor SchnakenburgSiegfried R. Waldvogelsubject
MolybdenumMolecular StructureOxidative CouplingChemistryStereochemistryOrganic ChemistryCarbon skeletonSequence (biology)DibenzocycloheptenesBond formationBiochemistryCatalysisLignansDominoChloridesCyclizationBenzene DerivativesOxidative coupling of methanePhysical and Theoretical ChemistryOxidation-Reductiondescription
A domino sequence involving various MoCl(5)-mediated oxidations followed by trapping and supposed [3,3]-sigmatropic rearrangement provides a fast access to the full carbon skeleton of metasequirin-B. A variety of different moieties R(1) and R(2) are tolerated.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-02-02 | Organic Letters |