Tetraspanins in infections by human cytomegalo- and papillomaviruses

6533b7ddfe1ef96bd127537e

RESEARCH PRODUCT

Tetraspanins in infections by human cytomegalo- and papillomaviruses

Diana Lieber Thorsten Lang Luise Florin Laura A. Fast

subject

Models Molecular 0301 basic medicine Cellular membrane Tetraspanins Cytomegalovirus Tetraspanin 24 Biology Endocytosis medicine.disease_cause Biochemistry Tetraspanin 28 Viral Proteins 03 medical and health sciences Tetraspanin medicine Humans Papillomaviridae CD151 Tetraspanin 30 Cell Membrane Papillomavirus Infections Cytomegalovirus Virus Internalization Virology Cell biology 030104 developmental biology Cytomegalovirus Infections embryonic structures Intracellular CD81

description

Members of the tetraspanin family have been identified as essential cellular membrane proteins in infectious diseases by nearly all types of pathogens. The present review highlights recently published data on the role of tetraspanin CD151, CD81, and CD63 and their interaction partners in host cell entry by human cytomegalo- and human papillomaviruses. Moreover, we discuss a model for tetraspanin assembly into trafficking platforms at the plasma membrane. These platforms might persist during intracellular viral trafficking.

year	journal	country	edition	language
2017-04-13	Biochemical Society Transactions

https://doi.org/10.1042/bst20160295

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