6533b7defe1ef96bd1276558
RESEARCH PRODUCT
Sarcoehrenbergilides D–F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi
Ahmed R. HamedAkemi UmeyamaShinji OhtaThomas EfferthMohamed-elamir F. HegazyAbdelsamed I. ElshamyMahmoud A. A. IbrahimTarik A. MohamedPaul W. Parésubject
Circular dichroismChemistryStereochemistryGeneral Chemical EngineeringCoralSarcophyton ehrenbergi02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesCytotoxic T cell0210 nano-technologyCytotoxicityHuman cancerdescription
A solvent extract of the soft coral Sarcophyton ehrenbergi afforded cembrene diterpenoids, sarcoehrenbergilid D–F (1–3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1–3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 | RSC Advances |