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RESEARCH PRODUCT
Reversed-phase high-performance liquid chromatography of proteins and polypeptides on polystyrene-coated silica supports
Vadim A. DavankovA. A. KurganovK.k. Ungersubject
ChromatographyResolution (mass spectrometry)Organic ChemistryCovalent bindingGeneral MedicineReversed-phase chromatographyBiochemistryHigh-performance liquid chromatographyAnalytical Chemistrychemistry.chemical_compoundchemistryPhase (matter)PolystyrenePorositySelectivitydescription
Abstract A new type of hydrolytically stable reversed-phase packing material prepared by multi-point covalent binding of polystyrene chains onto the surface of porous silica was examined in the high-performance liquid chromatography of proteins and polypeptides. Whereas wide-pore material was shown to give a rapid and efficient resolution of proteins, packings with smaller pores provided better selectivities for peptides.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-02-01 | Journal of Chromatography A |