6533b81ffe1ef96bd1277102

RESEARCH PRODUCT

Iodofluorination of alkenes and alkynes promoted by iodine and 4-iodotoluene difluoride

Barbara PanunziMarco TingoliPellegrino Conte

subject

Settore AGR/13 - Chimica AgrariaOrganic ChemistryDifluorideMarkovnikov's ruleHalogenationchemistry.chemical_elementGeneral MedicineIodineBiochemistrychemistryDrug DiscoveryPolymer chemistryOrganic chemistryHypervalent iodineElectrophilic iodinationFluoroiodoalkanesFluoroiodoalkenes

description

It was found that a mixt. of mol. iodine and 4-iodotoluene difluoride are useful to generate in situ the electrophilic iodine/nucleophilic fluorine (IF) couple that was able to add in a Markovnikov fashion and with prevalent anti-stereoselectivity to various alkenes and alkynes.

yearjournalcountryeditionlanguage
2006-05-02Tetrahedron Letters
https://doi.org/10.1016/j.tetlet.2005.11.029