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RESEARCH PRODUCT

Evidence for recombination between the pandemic GII.4 norovirus strains New Orleans 2009 and Sydney 2012

Vito MartellaGiovanni M. GiammancoAdriana CalderaroGianvito LanaveCanio BuonavogliaValentina TerioFabio TummoloFloriana BonuraMaria Cristina MediciLaura SaporitoCristiana CatellaS. De Grazia

subject

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaNorovirus GII.4 Sydney 2012 New Orleans 2009 recombinationvirusesMolecular Sequence DataBiologymedicine.disease_causeOpen Reading Framesfluids and secretionsViral geneticsVirologyPandemicmedicineHumansChildPandemicsCaliciviridae InfectionsRecombination GeneticGeneticsNorovirusvirus diseasesSequence Analysis DNAVirologyChild PreschoolNorovirusRNA Viral

description

ABSTRACT During 2012, a novel pandemic GII.4 norovirus variant, Sydney 2012, emerged worldwide. A signature of the variant was a GII.Pe ORF1, in association with GII.4 Apeldoorn 2008-like ORF2-ORF3 genes. We report the detection of recombinant GII.4 Sydney 2012 strains, possessing the ORF1 gene of the former pandemic variant New Orleans 2009.

10.1128/jcm.01847-13http://hdl.handle.net/10447/88043