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RESEARCH PRODUCT
Butyrate-Induced Growth Arrest of GH3-Cells is not Linked to a Distinct Morphological Phenotype
Gerd BrunnerGeorg Tschanksubject
chemistry.chemical_classificationCell typeChemistryCellSodium butyrateButyratePhenotypeCell biologychemistry.chemical_compoundmedicine.anatomical_structureMembranemedicinesense organsCytoskeletonGlycoproteindescription
N-butyric acid is known to be a potent proliferation-inhibitor of a great number of cell types, both normal and neoplastic (1). In many cases growth arrest is accompanied by striking changes in morphology, e.g. formation of cell processes or increased spreading (1). These changes can be traced back to altered glycolipide and glycoprotein patterns of the plasma membrane and to a reorganization of the cytoskeleton (2, 3).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1983-01-01 |