6533b81ffe1ef96bd1277d08

RESEARCH PRODUCT

Myocarditis in Mediterranean spotted fever: a case report and a review of the literature

Lucia SiracusaMarcello TrizzinoClaudia ColombaAnna GiammancoAntonio CascioClaudia Gioè

subject

0301 basic medicineMicrobiology (medical)medicine.medical_specialtyPediatricsMyocarditisHeart rhythm disorders030106 microbiologyCase ReportDiseaseMediterraneanMicrobiology03 medical and health sciencesPericarditisZoonosis0302 clinical medicineCase fatality rateMedicinespotted030212 general & internal medicineconoriiIntensive care medicineBlood/Heart and Lymphaticsfeverbiologybusiness.industryMortality rateMediterranean; conorii; fever; myocarditis; rickettsia; spottedmedicine.diseasebiology.organism_classificationrickettsiaSpotted fevermyocarditimyocarditisbusinessRickettsia conorii

description

Introduction: Mediterranean spotted fever (MSF) is a tick-borne acute febrile disease caused by Rickettsia conorii. Most cases follow a benign course, with a case fatality rate of 3–7 % among hospitalized patients. Complications are described mainly in adult patients and include hepatic, renal, neurological and cardiac impairment. Among cardiac complications, pericarditis, myocarditis and heart rhythm disorders are uncommon complications in MSF and only a few cases have been reported in the literature. Case Presentation: We describe a new case of acute myocarditis complicating MSF in an immunocompetent adult patient without risk factors for severe MSF. Conclusion: Myocarditis is an uncommon but severe complication of MSF. Clinicians should be aware of a possible cardiac involvement in patients with MSF. Close monitoring and an aggressive approach are essential to reduce mortality rates of MSF.

10.1099/jmmcr.0.005039http://europepmc.org/articles/PMC5330236