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RESEARCH PRODUCT
Distribution of emm types among group A streptococcal isolates from Serbia.
Marija MarkovićVera MijacLazar RaninNatasa OpavskiC. HeegRalf René Reinertsubject
Microbiology (medical)DNA BacterialMaleGenotypemedicine.drug_classTetracyclineStreptococcus pyogenesErythromycinDrug resistanceMicrobial Sensitivity TestsBiologymedicine.disease_causeMicrobiologyMacrolide Antibioticsresistance03 medical and health sciences0302 clinical medicinestomatognathic systemStreptococcal InfectionsGenotypeotorhinolaryngologic diseasesmedicineHumans030212 general & internal medicine0303 health sciencesAntigens BacterialMolecular EpidemiologyPolymorphism GeneticSuperantigensMolecular epidemiology030306 microbiologyStreptococcusGeneral Medicinebacterial infections and mycosesDNA Fingerprinting3. Good healthAnti-Bacterial Agentsstomatognathic diseasesInfectious Diseasesemm typeStreptococcus pyogenesFemaleCarrier ProteinsSerbiamedicine.drugBacterial Outer Membrane Proteinsdescription
AbstractThis is the first study concerning the molecular epidemiology of group A streptococcus in Serbia and includes 145 isolates from patients with various infections during the period 2001–2007. The emm types, superantigen profile and susceptibility pattern were determined. Among 31 emm types identified, the most prevalent were emm6, emm12, emm1, and emm58. All isolates showed uniform antimicrobial susceptibility to all tested antibiotics, with the exception of tetracycline and erythromycin (41% and 0.7% resistant strains, respectively). Significant heterogeneity of emm types was found, with a high frequency of emm6 and emm58, as well as a considerable prevalence of tetracycline resistance, and a low level of macrolide resistance.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-03-01 | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |