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RESEARCH PRODUCT
Molecular modeling and experimental studies on structure and NMR parameters of 9-benzyl-3,6-diiodo-9H-carbazole
Zdzisław DaszkiewiczKrzysztof EjsmontTeobald KupkaStephan P. A. SauerKlaudia Radula-janiksubject
Relativistic EffectsNICSMolecular modelGIAO NMR CalculationsDFT calculationsZORAchemistry.chemical_compoundComputational chemistrycarbazoleFaculty of ScienceHOMAMolecule13 C NMR spectra/dk/atira/pure/core/keywords/TheFacultyOfSciencePhysical and Theoretical ChemistryBenzeneHarmonic oscillator9-Benzyl-3CarbazoleChemical shiftAromaticityQuantum Chemistry6-diiodo-9H-carbazoleCondensed Matter Physicscomputational chemistryNMR spectrocopychemistryPhysical chemistryDensity functional theoryX-ray structureNMR; chemical shiftdescription
A combined experimental and theoretical study has been performed on 9-benzyl-3,6-diiodo-9H-carbazole. Experimental X-ray (100.0 K) and room-temperature 13C NMR studies were supported by advanced density functional theory (DFT) calculations. The non relativistic structure optimization was performed and the 13C nuclear magnetic shieldings were predicted at the relativistic level of theory using the Zeroth Order Regular Approximation (ZORA). The changes in the benzene and pyrrole rings compared to the unsubstituted carbazole or the parent molecules were discussed in terms of aromaticity changes using the harmonic oscillator model of aromaticity (HOMA) and the nucleus independent chemical shift (NICS) indexes. Theoretical relativistic calculations of chemical shifts of carbons C3 and C6, directly bonded to iodine atoms, produced a reasonable agreement with experiment (initial deviation from experiment of 41.57 ppm dropped to 5.6 ppm). A good linear correlation between experimental and theoretically predicted structural and NMR parameters was observed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-11 | Structural Chemistry |