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RESEARCH PRODUCT

Ketogenic diet, physical activity, and hypertension—a narrative review

Edoardo PireraAntonino TuttolomondoSilvio BuscemiDavide CorleoAntonio PintoDomenico Di RaimondoGaia MusiariGiuliana Rizzo

subject

Settore MED/09 - Medicina Internamedicine.medical_treatmentphysical activity030209 endocrinology & metabolismReview030204 cardiovascular system & hematologyEssential hypertensionEssential hypertension03 medical and health sciences0302 clinical medicineWeight lossAerobic capacityIntervention (counseling)Environmental healthHumansMedicineTX341-641Healthy LifestyleSettore MED/49 - Scienze Tecniche Dietetiche ApplicateExerciseGlycemicNutrition and DieteticsNutrition. Foods and food supplybusiness.industryKetogenic dietmedicine.diseaseObesityBlood pressureCardiovascular DiseasesHeart Disease Risk FactorsHypertensionBlood pressurePhysical activity.Metabolic syndromemedicine.symptomDiet KetogenicbusinessFood ScienceKetogenic diet

description

Several studies link cardiovascular diseases (CVD) with unhealthy lifestyles (unhealthy dietary habits, alcohol consumption, smoking, and low levels of physical activity). Therefore, the strong need for CVD prevention may be pursued through an improved control of CVD risk factors (impaired lipid and glycemic profiles, high blood pressure, and obesity), which is achievable through an overall intervention aimed to favor a healthy lifestyle. Focusing on diet, different recommendations emphasize the need to increase or avoid consumption of entire classes of food, with only partly known and only partly foreseeable consequences on the overall level of health. In recent years, the ketogenic diet (KD) has been proposed to be an effective lifestyle intervention for metabolic syndrome, and although the beneficial effects on weight loss and glucose metabolism seems to be well established, the effects of a prolonged KD on the ability to perform different types of exercise and the influence of KD on blood pressure (BP) levels, both in normotensives and in hypertensives, are not so well understood. The objective of this review is to analyze, on the basis of current evidence, the relationship between KD, regular physical activity, and BP.

10.3390/nu13082567http://hdl.handle.net/10447/518102