6533b820fe1ef96bd1279874

RESEARCH PRODUCT

Gabapentin in the treatment of hemifacial spasm

P. CapusC. MarchiniL. MucchiutOrnella DanieleG. CaravagliosE. Natale

subject

Involuntary movementChemotherapymedicine.medical_specialtyGabapentinbusiness.industrymedicine.medical_treatmentTreatment outcomeGeneral Medicinemedicine.diseaseBotulinum toxinnervous system diseasesSurgerybody regionsClinical trialstomatognathic diseasesAnticonvulsantNeurologyAnesthesiaotorhinolaryngologic diseasesMedicinecardiovascular diseasesNeurology (clinical)businessHemifacial spasmmedicine.drug

description

Objectives To evaluate the efficacy of gabapentin in the treatment of hemifacial spasm. Material and methods Twenty-three patients with hemifacial spasm not suitable for surgery or therapy with botulinum toxin were treated with gabapentin. The main efficacy parameter was the percentage of spasm reduction. Results A clinically significant reduction of spasms was obtained by 16 patients. Conclusion Gabapentin was effective and safe in reducing hemifacial spasm in 16 out 23 (69.6%) patients.

https://doi.org/10.1034/j.1600-0404.2001.104002110.x