6533b820fe1ef96bd1279a10

RESEARCH PRODUCT

Hypertonic Stress and Amino Acid Deprivation Both Increase Expression of mRNA for Amino Acid Transport System A

Andrea CavazzoniSilvia DesenzaniMara BonelliAngelo F. BorghettiRoberta AlfieriKenneth P. WheelerPier Giorgio Petronini

subject

Amino Acid Transport System APhysiologyCHO CellsBiologyCricetulusOsmotic PressureCricetinaeAnimalsHumansOsmotic pressureRNA MessengerAmino AcidsLetter to the Editorchemistry.chemical_classificationRegulation of gene expressionMessenger RNAChinese hamster ovary cellbiology.organism_classificationAmino acidGene Expression RegulationHypotonic SolutionschemistryBiochemistryHypertonic StressTonicityCricetulus

description

The activity of amino acid transport system A ([Oxender and Christensen, 1963][1]) is regulated in a variety of different ways, the best studied being the increases of its activity caused by starving cells of amino acids or by exposing them to hypertonicity (for review see [McGivan and Pastor-

https://doi.org/10.1085/jgp.200409195