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RESEARCH PRODUCT
Objectively measured physical activity profile and cognition in Finnish elderly twins
Henri Vähä-ypyäNoora LindgrenHarri SievänenEero VuoksimaaUrho M. KujalaJuha O. RinnePaula Iso-markkuJaakko KaprioKatja WallerKauko Heikkiläsubject
GerontologykognitioTwinsphysical activityliikunta3124 Neurology and psychiatry0302 clinical medicineCognitionsedentary behaviorAccelerometryMedicine030212 general & internal medicine315 Sport and fitness sciences10. No inequalityta3152. Zero hungerexerciseCognitionta3141Sedentary behaviorta3142Psychiatry and Mental healthagedCohortikääntyneetfyysinen aktiivisuusgenetiikkaPhysical activityaktigrafiaistuminen03 medical and health sciencesGeneticsaccelerometryDementiaExerciseAgedperinnöllisyystiedebusiness.industryPhysical activityActigraphyFeatured Articlemedicine.diseaseActigraphyConfidence intervalta3124kaksosetSedentary behaviorDementiaNeurology (clinical)businessBody mass index030217 neurology & neurosurgerydementiadescription
Introduction We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins. Methods This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer. Results In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: β-estimate, −0.21 [95% confidence intervals, −0.42 to −0.003]; light physical activity: β-estimate, 0.30 [95% confidence intervals, 0.02–0.58]). In within-family models, there were no significant linear associations between objectively measured PA and cognition. Discussion Objectively measured light physical activity and SB are associated with cognition in Finnish twins in their seventies, but the associations were attributable to genetic and environmental selection.
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2018-01-01 |